March 10, 2024
¿Ha aumentado la incidencia del cáncer en el mundo?

Se pronostica que para 2050 los casos de cáncer aumentarán un 77%. Encontrar una cura para esta enfermedad parece ser la causa de la especie humana. ¿Cuáles son los tratamientos que existen hoy en día?, ¿por qué no hemos podido encontrar una cura?
Para este capítulo hablamos con el médico radiólogo Germán Arango; con el exministro de salud Alejandro Gaviria; Rafael Sánchez París, Director ejecutivo del Centro de Tratamiento e Investigación sobre cáncer Luis Carlos Sarmiento Angulo; y con Lina María Trujillo, subdirectora de Atención Médica y Docencia del Instituto Nacional de Cancerología.
WEBVTT
1
00:00:01.080 --> 00:00:06.599
The day to day is full of
urgent news, noise, polemics and fanfare.
2
00:00:06.599 --> 00:00:11.240
But for the quiet, the analysis
and what we like to call slow
3
00:00:11.439 --> 00:00:18.719
- cooking journalism are my questions.
A half- hurry program made by KFAM
4
00:00:19.079 --> 00:00:32.280
inspiring smiles. It is predicted that
by two thousand and fifty cancer cases will
5
00:00:32.320 --> 00:00:37.479
increase by seventy- seven percent.
Finding a cure for this disease seems to
6
00:00:37.560 --> 00:00:41.840
be the cause of the human species. What are the treatments that exist today,
7
00:00:41.960 --> 00:00:47.159
why we have not been able to
find a cure for this chapter.
8
00:00:47.479 --> 00:00:54.479
We spoke with radiologist Germán Arango,
with former Health Minister Alejandro Gaviria. Rafael
9
00:00:54.560 --> 00:01:00.560
Sánchez Paris, Executive Director of the
Center for Cancer Treatment and Research, Scarlos
10
00:01:00.600 --> 00:01:06.719
Sarmiento Angulo and Lina MarÃa Trujillo,
Deputy Director of Medical Care and Teaching at
11
00:01:06.760 --> 00:01:11.840
the National Cancer Institute. I am
Roberto Pombo and this is chapter seventy-
12
00:01:12.000 --> 00:01:19.359
eight of my questions. Welcome.
The human has taken all his history,
13
00:01:19.840 --> 00:01:25.760
understanding himself, the world around him
and the connection between all. Since the
14
00:01:25.879 --> 00:01:30.799
arbors of our conscience, we have
asked ourselves questions and it was not enough
15
00:01:30.879 --> 00:01:34.040
for us to be bipeds and to
have opposable thumbs. We have explored the
16
00:01:34.439 --> 00:01:38.840
world all its seas and depths,
volcanoes and its wild force and glaciers,
17
00:01:40.120 --> 00:01:47.519
jungle deserts. We study every species
with which we share the planet at some
18
00:01:47.599 --> 00:01:49.239
point in history. It wasn'
t enough for us what was around us.
19
00:01:49.760 --> 00:01:55.599
Then we looked up and looked for
explanations to what was beyond our reach
20
00:01:55.640 --> 00:02:00.920
at the time. So someone once
created a device to find out what those
21
00:02:00.040 --> 00:02:05.920
lights were all about, shining in
what we call heaven. We saw them
22
00:02:06.000 --> 00:02:10.800
moving at a pace we could predict. Then we gave them names, finding
23
00:02:10.840 --> 00:02:15.199
their characteristics. We realized our place
in the Universe, the immensity and infinity,
24
00:02:16.000 --> 00:02:23.000
of what was beyond the earth.
We have found explanations for the universe,
25
00:02:23.319 --> 00:02:28.879
its galaxies, black holes, nebulae
and stars. All that wasn'
26
00:02:29.000 --> 00:02:31.280
t enough for us. And just
as someone created a telescope to see and
27
00:02:31.360 --> 00:02:37.439
understand what was at distances and times
almost impossible to reach. Someone created a
28
00:02:37.479 --> 00:02:43.840
microscope to see what was inside us. So we did the same thing at
29
00:02:43.840 --> 00:02:46.159
quantum level, that is, not
outwards, but inwards, at the level
30
00:02:46.159 --> 00:02:52.560
of molecules and atoms. At one
point we said that that was the limit
31
00:02:52.560 --> 00:02:55.599
point, which was indivisible, the
micro thing that existed. However, as
32
00:02:55.840 --> 00:03:00.080
it seems, custom was temporary to
and someone else discovered that it could be
33
00:03:00.159 --> 00:03:07.159
seen beyond the atom and later divided
it. I am dazzled to see the
34
00:03:07.199 --> 00:03:09.960
level of knowledge we have acquired as
a species. It will seem that there
35
00:03:10.039 --> 00:03:15.120
is nothing impossible for this wonderful species
that we are, with its lights and
36
00:03:15.120 --> 00:03:19.000
shadows. And although out there,
in space so far and on a macro
37
00:03:19.120 --> 00:03:23.879
scale, there are aspects that seem
to overcome us and determine our existence,
38
00:03:24.080 --> 00:03:30.120
although around us there are depths and
elements that threaten our existence. It is
39
00:03:30.199 --> 00:03:34.479
at the atomic level within us that
there is a phenomenon that owns our fears
40
00:03:34.560 --> 00:03:42.560
and that today is a threat to
humanity, cancer cells. Cancer is not
41
00:03:42.599 --> 00:03:46.560
something new. Human beings and other
animals have had cancer throughout history and there
42
00:03:46.599 --> 00:03:53.599
are records of that disease in fossils
and most holy scriptures. Some of the
43
00:03:53.680 --> 00:03:59.159
first cancer tests are among fossilized bone
tumors, human mummies from ancient Egypt,
44
00:03:59.520 --> 00:04:05.120
and ancient manuscripts. For example,
mummies have been found with growths that suggest
45
00:04:05.199 --> 00:04:13.240
bone cancer called hostium sarcoma. The
oldest description you have did not include the
46
00:04:13.280 --> 00:04:16.800
word cancer was discovered in Egypt and
dates back to the year three thousand BC,
47
00:04:16.959 --> 00:04:21.800
in a papyrus known as Papyrus Edwin
Smith, which is part of a
48
00:04:21.920 --> 00:04:27.879
book on trauma surgery and is said
to be the first surgical treatise in history.
49
00:04:29.959 --> 00:04:34.920
This document describes eight cases of breast
tumors or ulcers that were removed by
50
00:04:35.000 --> 00:04:42.639
cauterization with a tool called a fire
drill. The paper says about the disease
51
00:04:43.240 --> 00:04:47.160
there is no treatment. It was
not until the 19th century, when the
52
00:04:47.160 --> 00:04:53.240
anesthesia appeared that the first surgeries were
performed to remove some types of cancer.
53
00:04:53.839 --> 00:04:57.800
But, even though this disease has
shared so much time with humans, understanding
54
00:04:57.800 --> 00:05:02.079
it has not been easy. One
of the many statements that have been made
55
00:05:02.120 --> 00:05:08.800
on the subject is that we all
have cancer cells, but that' s
56
00:05:08.920 --> 00:05:13.959
how we go about parts. This
disease arises from random genetic changes, called
57
00:05:14.040 --> 00:05:20.079
mutations within healthy cells acquired over time. These mutations can occur for several reasons,
58
00:05:20.240 --> 00:05:25.839
such as lifestyle choices, family predispositions, long- term existing health conditions,
59
00:05:26.040 --> 00:05:32.279
or even exposing hazardous chemicals. As
mutated cells build up, they become
60
00:05:32.360 --> 00:05:40.000
cancerous. A cell that is able
to grow without control accumulates errors in its
61
00:05:40.079 --> 00:05:46.199
DNA code, which makes a gene
or set of genes malfunction. If the
62
00:05:46.279 --> 00:05:50.480
cell also loses certain safety mechanisms this
pushes it toward cancer. In other words,
63
00:05:51.199 --> 00:05:56.879
several factors need to come together to
make a cell cancerous. And any
64
00:05:57.000 --> 00:06:00.600
cell in the body has the potential
to do so. It can be divided
65
00:06:01.040 --> 00:06:06.160
if it accumulates errors with certain genes
and if these failures cause it to grow
66
00:06:06.160 --> 00:06:12.519
out of control. According to doctors
Hugur Shain and Oslem Duressi, founders of
67
00:06:12.519 --> 00:06:16.839
the biotechnology company Biontech, these random
genetic changes that occur in cancer cells arise
68
00:06:16.920 --> 00:06:24.120
two implications. The first is that
each cancer is as unique as the individual
69
00:06:24.160 --> 00:06:28.199
it affects, that is, that
even those people who are diagnosed with the
70
00:06:28.279 --> 00:06:33.680
same type of cancer have only a
fraction of shared mutations. And the second
71
00:06:33.759 --> 00:06:39.480
implication is that each tumor is a
intricate tapestry of billions of different cells that
72
00:06:39.480 --> 00:06:45.279
constantly learn to adapt, to evade
the immune system and to resist the therapeutic
73
00:06:45.319 --> 00:06:50.240
strategies that medicine and technology has investigated
And it is that possible cures therapies,
74
00:06:50.879 --> 00:06:58.040
varying shock treatments have not been lacking
in history. Since surgeries to remove tumors,
75
00:06:58.240 --> 00:07:00.639
the use of radiation and official artis
intelligence have been part of human innovation
76
00:07:00.639 --> 00:07:09.759
to combat that inner enemy. I
looked for Dr Rafael Sánchez Paris, Executive
77
00:07:09.879 --> 00:07:14.360
Director of the Cancer Treatment and Research
Center, Juis Carlos Sarmiento Angulou, to
78
00:07:14.399 --> 00:07:18.680
better answer the big question why is
it so difficult to find a cure for
79
00:07:18.759 --> 00:07:26.399
cancer? This he told me,
cancer is not just a disease. It
80
00:07:26.480 --> 00:07:34.399
is a group of really different diseases, caused by factors sometimes different from each
81
00:07:34.519 --> 00:07:41.639
other. Therefore, at the outset
there are some more curable than others.
82
00:07:41.680 --> 00:07:47.160
In addition, today the number of
patients with advanced disease is higher than with
83
00:07:47.279 --> 00:07:55.639
early disease. When cancer is diagnosed
early, the cure percentage is higher and
84
00:07:55.720 --> 00:08:01.480
this is directly related to timely access
to health services and self- care.
85
00:08:05.759 --> 00:08:13.759
Finally, the genomic changes within the
disease are dynamic and progressive. That is,
86
00:08:15.639 --> 00:08:20.680
cells learn to survive the treatments given, which complements treatment over time.
87
00:08:26.120 --> 00:08:31.279
A recent report was published in the
journal b m Jota Oncology, which concludes,
88
00:08:31.720 --> 00:08:35.759
among other things, that the global
incidence of early- onset cancer increased
89
00:08:35.879 --> 00:08:39.120
by seventy- nine comma one percent, and the number of early- oncology
90
00:08:39.159 --> 00:08:45.879
deaths increased by twenty- seven comma
seven percent between one thousand nine hundred ninety
91
00:08:46.240 --> 00:08:50.080
- two thousand nineteen. In more
concise terms, the number of people under
92
00:08:50.120 --> 00:08:54.639
the age of 50 diagnosed with this
disease worldwide has increased by almost eighty percent
93
00:08:54.879 --> 00:09:01.080
in the last three decades alone,
and the findings of the study do not
94
00:09:01.080 --> 00:09:07.360
stop there. Projections indicated that the
overall number of incidences and deaths from early
95
00:09:07.879 --> 00:09:11.759
- onset cancer would increase by thirty- one percent and twenty- one percent
96
00:09:11.879 --> 00:09:16.519
by two thousand thirty, respectively.
And excuse me for all the bad news.
97
00:09:16.600 --> 00:09:20.840
But, according to the World Health
Organization, more than thirty- five
98
00:09:20.879 --> 00:09:24.480
million new cases are predicted for two
thousand fifty, an increase of seventy-
99
00:09:24.000 --> 00:09:28.799
seven percent, compared with the estimated
twenty million cases for two thousand twenty-
100
00:09:28.279 --> 00:09:35.399
two. All these figures of the
rapidly growing global burden of cancer reflect the
101
00:09:35.519 --> 00:09:41.639
ageing and growth of the world population, as well as changes in people'
102
00:09:41.759 --> 00:09:45.720
s exposure to risk factors of which
several are associated with socio- economic development.
103
00:09:48.879 --> 00:09:54.320
All these numbers for the future are
not encouraging A little over a month
104
00:09:54.320 --> 00:09:58.600
ago, the International Agency for Cancer
Research published the latest estimates of the global
105
00:09:58.679 --> 00:10:05.000
burden of cancer, in which they
found data like First, in only two
106
00:10:05.080 --> 00:10:09.039
thousand twenty- two there were twenty
million new cases and nine seven million deaths
107
00:10:09.039 --> 00:10:16.600
from this disease. Second, about
one in five people develop cancer throughout their
108
00:10:16.679 --> 00:10:20.600
lives and finally, about one in
nine men and one in twelve women die
109
00:10:20.799 --> 00:10:30.279
from the disease. All these numbers
of such impressive proportions leave me with many
110
00:10:30.279 --> 00:10:35.639
questions, but especially one way to
reverse all these estimates about the future incidence
111
00:10:35.720 --> 00:10:41.159
of cancer. I looked for arina
MarÃa Trujillo and assistant director of medical care
112
00:10:41.200 --> 00:10:46.120
and teaching at the National Cancer Institute. To answer this, he told me
113
00:10:46.200 --> 00:10:50.360
the first thing is to declare that
cancer is not a single disease. It
114
00:10:50.440 --> 00:10:56.159
is a word that groups different diseases
that have different origins, different causalities and,
115
00:10:56.399 --> 00:11:01.440
by that of different approach, not
only of annassic treatment, then there
116
00:11:01.440 --> 00:11:05.919
is no common strategy. The only
thing we could talk about is that we
117
00:11:05.039 --> 00:11:11.480
could change in a relatively feasible time
frame according to the calculations of interim neck
118
00:11:11.480 --> 00:11:16.600
cancer, cancer whose torino has a
global elimination strategy that, in fact,
119
00:11:16.759 --> 00:11:22.200
Cartagena is the headquarters of the Global
Forum on the Elimination of Cervical Cancer,
120
00:11:22.440 --> 00:11:26.559
in which three strategies are proposed.
Thanks to the fact that with terino neck
121
00:11:26.639 --> 00:11:31.120
cancer we know who produces it,
we have tools to diagnose it before it
122
00:11:31.200 --> 00:11:33.080
becomes cancer and we have how to
treat it properly. Once it' s
123
00:11:33.159 --> 00:11:37.720
a cancer, which we have to
prevent, vaccines against the human papillomavirus,
124
00:11:37.039 --> 00:11:41.320
which is the causal people, which
we have to diagnose in a timely manner
125
00:11:41.360 --> 00:11:46.000
before it' s a cancer,
papilloma virus tests and psitologies and we have
126
00:11:46.080 --> 00:11:50.919
how to treat it. Colombia has
enough staff and enough technology to cope with
127
00:11:52.039 --> 00:11:58.159
the different stages of cancer of Colombian
women, although cancer, as it already
128
00:11:58.200 --> 00:12:03.440
says, is an anti- disease
to what this alarming increase is due to,
129
00:12:03.639 --> 00:12:07.799
According to the authors of the study
published in bm J, oncology.
130
00:12:07.120 --> 00:12:11.279
Genetic factors are likely to influence,
but diets rich in meat, red and
131
00:12:11.399 --> 00:12:16.320
salt and low without fruits and milk, in addition to alcohol and tobacco consumption,
132
00:12:16.440 --> 00:12:20.240
are the main risk factors behind the
most common cancers among those under 50
133
00:12:20.360 --> 00:12:24.440
years of age, in addition to
physical inactivity, excess weight and high blood
134
00:12:24.480 --> 00:12:31.720
sugar levels. According to this research, I quote the changes in diet,
135
00:12:33.159 --> 00:12:35.799
lifestyle and environment since the beginning of
the 20th century that have led to an
136
00:12:35.799 --> 00:12:43.840
increase in rates and obesity. Physical
inactivity, Westernized diets, and environmental pollution
137
00:12:43.879 --> 00:12:48.279
may have affected the incidence of early
onset cancer. In addition, alcohol,
138
00:12:48.639 --> 00:12:56.480
smoking and harmful exposures during pregnancy may
also have affected closing quotes and make a
139
00:12:56.559 --> 00:13:01.120
lot of sense. Just think about
how I change the human' s life,
140
00:13:01.159 --> 00:13:03.639
his work routines, or the way
we feed or consume products such as
141
00:13:03.720 --> 00:13:11.000
alcohol, nicotine, or ultraprocessed edibles. On the latter, a study by
142
00:13:11.000 --> 00:13:16.600
the University of Viennam in collaboration with
the International Agency for Cancer Research found that
143
00:13:16.600 --> 00:13:20.279
the higher the consumption of ultraprocessed foods, the greater the risk of suffering a
144
00:13:20.399 --> 00:13:28.279
combination of chronic diseases such as cancer, diabetes or heart disease. Another of
145
00:13:28.320 --> 00:13:33.240
these changes in modern life that have
helped to increase cases of this disease is
146
00:13:33.279 --> 00:13:39.919
air pollution, as if global warming
was no longer enough. At the presidential
147
00:13:39.000 --> 00:13:45.919
symposium itself two thousand twenty- two, Professor Charles Schanton of the Francis Creek
148
00:13:45.919 --> 00:13:50.080
Institute, a biomedical research center in
London, presented an investigation that highlighted that
149
00:13:50.159 --> 00:13:56.440
the same particles that contribute to climate
change are impacting human health through an important
150
00:13:56.440 --> 00:14:03.360
mechanism that causes cancer in lung cells. The Lancet Commission on Pollution and Health
151
00:14:03.679 --> 00:14:07.120
established that all forms of pollution cause
forty- three percent of lung cancer deaths.
152
00:14:09.720 --> 00:14:13.679
Air pollution alone causes twenty- nine
percent of all lung cancer deaths and
153
00:14:13.679 --> 00:14:18.399
clear estimates give, according to WHO, ninety- nine percent are breathing unhealthy
154
00:14:18.399 --> 00:14:26.399
air. As Dr Emmanuel Ricard told
him by the voice of the French League
155
00:14:26.600 --> 00:14:31.759
against Cancer in the medium Frans van
Cat, it is mainly about pollution by
156
00:14:31.840 --> 00:14:37.440
fine particles and the gases emitted by
the saying are one of the main sources
157
00:14:37.440 --> 00:14:41.480
of these particles. However, a
study published in the British journal of cancer,
158
00:14:41.960 --> 00:14:48.440
the greatest risk factor for most cancers
is simply aging. According to the
159
00:14:48.519 --> 00:14:54.200
study, more than three quarters of
all people diagnosed with this disease in the
160
00:14:54.320 --> 00:14:58.559
UK are sixty years of age or
older, and this is because cancer is
161
00:14:58.639 --> 00:15:03.559
a disease of our genes. Fragments
of the DNA Code that contain instructions for
162
00:15:03.639 --> 00:15:09.360
all microscopic machinery within our cells and
over time, errors accumulate in this code
163
00:15:09.600 --> 00:15:13.600
and scientists can now see them imprinted
on the cancer DNA, and it is
164
00:15:13.639 --> 00:15:20.200
these errors that can drive a cell' s journey. They are reached,
165
00:15:22.759 --> 00:15:26.720
but not all are bad news.
According to the nation' s annual report
166
00:15:26.720 --> 00:15:31.039
on the cancer situation in general,
mortality rates for this disease decreased by an
167
00:15:31.120 --> 00:15:35.679
average of two comma three per cent
per year among men and an average of
168
00:15:35.759 --> 00:15:41.399
one comma nine per cent per year
among women. The overall cancer mortality rate
169
00:15:41.480 --> 00:15:46.039
in the United States declined by one
third between one thousand nine hundred and ninety
170
00:15:46.279 --> 00:15:50.080
- one and two thousand nineteen.
This is largely because fewer people smoke and
171
00:15:50.120 --> 00:15:54.759
develop lung cancer, also because as
screening tests, prevention and treatments have improved
172
00:15:54.799 --> 00:16:00.039
for all types of cancer it is, this decrease has continued and even accelerated.
173
00:16:03.039 --> 00:16:08.039
The national cancer mortality rate is falling
by about two percent each year and
174
00:16:08.120 --> 00:16:15.639
in Colombia the survival of childhood cancer
is sixty percent. Early detection is one
175
00:16:15.720 --> 00:16:19.840
of the ways in which it can
help more people survive this disease and for
176
00:16:19.840 --> 00:16:26.120
this purpose, it seems that artificial
intelligence can play a key role. It
177
00:16:26.240 --> 00:16:30.559
couldn' t be used just to
make fake videos of politicians. And that
178
00:16:30.600 --> 00:16:36.720
' s because, according to research
published in The Lancet Oncology suggests that artificial
179
00:16:36.799 --> 00:16:41.960
intelligence could diagnose cancer with twice as
much accuracy as a doctor' s biopsy.
180
00:16:45.159 --> 00:16:48.360
I looked for radiologist Germán Arango,
who already uses this technology for medical
181
00:16:48.440 --> 00:16:53.519
purposes, and asked him how artificial
intelligence can help detect cancer in a timely
182
00:16:53.559 --> 00:17:00.120
manner. This he told me.
Artificial intelligence can be significantly helped in early
183
00:17:00.159 --> 00:17:06.279
detection of cancer through various methods and
applications. The first and most important of
184
00:17:06.359 --> 00:17:11.279
these is in the analysis of diagnostic
medical images, where, especially deep learning
185
00:17:11.400 --> 00:17:18.200
has shown remarkable effectiveness in the analysis
of diagnostic medical images. Like MRIs,
186
00:17:19.039 --> 00:17:25.759
CT scans, mammograms, X-
rays. Artificial intelligence algorithms can detect abnormalities
187
00:17:25.799 --> 00:17:30.640
in images that can be indicative of
cancer, often with the accuracy that equals
188
00:17:30.720 --> 00:17:36.599
or exceeds that of human specialists.
Here it is important to highlight a new
189
00:17:36.720 --> 00:17:41.519
technique, which is total body resonance
or diamar powder, which is an advanced
190
00:17:41.559 --> 00:17:45.160
imaging technique that allows you to obtain
detailed images of the whole body in a
191
00:17:45.160 --> 00:17:49.319
single exposure, being especially valuable in
the early detection of cancer. The editing
192
00:17:49.359 --> 00:17:55.799
of artificial intelligence to the diagnostic process
of this technique substantially increases its performance and
193
00:17:55.799 --> 00:17:59.559
accuracy, taking into account that it
generates large volumes of information. Other fronts
194
00:17:59.599 --> 00:18:06.039
where artificial intelligence contributes to the early
diagnosis of cancer. These are pattern analyses,
195
00:18:06.559 --> 00:18:11.720
assisted diagnosis, personalization of detection,
research and development, and continuous dying.
196
00:18:12.759 --> 00:18:17.680
In short, artificial interedency is transforming
the field of ecological diagnosis, improving
197
00:18:17.839 --> 00:18:22.200
accuracy and efficiency in early scope detection, which can lead to better prognosis and
198
00:18:22.200 --> 00:18:32.319
higher survival rates for patients. Attempts
to overcome this disease do not begin or
199
00:18:32.440 --> 00:18:37.640
end with artificial intelligence. From surgery
to chemotherapy, treatments have become more friendly
200
00:18:37.640 --> 00:18:42.599
or less invasive. For example,
if someone was diagnosed with breast cancer 100
201
00:18:42.640 --> 00:18:48.079
years ago, doctors had to take
drastic measures, such as removing the entire
202
00:18:48.119 --> 00:18:52.039
breast, along with the underlying pectoral
muscles and all the lymph nodes in the
203
00:18:52.079 --> 00:18:57.799
armpit. However, in nineteen hundred
and sixty, a type of surgery was
204
00:18:57.920 --> 00:19:03.359
discovered that was less invasive or snomizing
the side effects. The same has happened
205
00:19:03.400 --> 00:19:07.680
with other treatments, such as radiation
therapy and chemotherapy, which over time have
206
00:19:07.839 --> 00:19:14.640
refined and refined their procedures to minimize
side effects. And, as I mentioned
207
00:19:14.720 --> 00:19:18.680
before, as well as our faces
and our actillary footprints, each case of
208
00:19:18.759 --> 00:19:23.559
cancer is unique. Researchers have discovered
many ways to reduce the negative impacts of
209
00:19:23.640 --> 00:19:29.960
treatments, adapting them to individual needs
such as modulated intensity radiation therapy, in
210
00:19:29.960 --> 00:19:33.960
which radiation rays vary in intensity strength, allowing them to shape to point to
211
00:19:33.000 --> 00:19:37.359
a precise area, either in the
exact form of a tumor, if used
212
00:19:37.400 --> 00:19:41.160
to reduce it before surgery, or
the immediate area around where there was until
213
00:19:41.359 --> 00:19:48.759
the last. In fact, the
pandemic left something good and it was that
214
00:19:48.799 --> 00:19:55.079
research to develop the vaccine against covid
nineteen inspired the use of this same molecule
215
00:19:55.160 --> 00:20:00.440
to create a vaccine against pancras cancer. Last year the results of the first
216
00:20:00.480 --> 00:20:03.880
trials in patients, a group of
sixteen people in a first batch of trials
217
00:20:03.920 --> 00:20:11.799
showed promising results. Fifty percent of
the patients had positive results for this trial
218
00:20:11.839 --> 00:20:18.599
had to create a personalized vaccine for
each patient. However, and even though
219
00:20:18.599 --> 00:20:22.160
different treatments have been tried for the
many types of cancer, accessing them is
220
00:20:22.440 --> 00:20:30.200
not always easy. The WHO Global
Survey on Universal Health Coverage and Cancer shows
221
00:20:30.279 --> 00:20:33.400
that only thirty- nine per cent
of participating countries covered basic aspects of cancer
222
00:20:33.480 --> 00:20:38.079
management as part of their basic health
services funded for all citizens, health benefit
223
00:20:38.160 --> 00:20:44.160
packages, and only 28 per cent
of participating countries additionally covered care for people
224
00:20:44.160 --> 00:20:48.359
in need of palliative care, including
pain relief in general, and not just
225
00:20:48.400 --> 00:20:59.079
cancer- related care. The case
of Colombia is not the worst, but
226
00:20:59.160 --> 00:21:02.519
neither is the best. According to
an article by the University of Rosario,
227
00:21:03.000 --> 00:21:07.519
cancer mortality rates are higher in Colombia
due to greater barriers to early diagnosis,
228
00:21:07.920 --> 00:21:11.599
which is that mortality rates are higher
in middle- and low- income countries,
229
00:21:11.799 --> 00:21:15.480
which shows that there are fewer preventive
actions and greater access barriers to diagnosis
230
00:21:15.599 --> 00:21:25.000
and early initiation of treatment. According
to the newspaper, La República with data
231
00:21:25.039 --> 00:21:29.720
from ASEMI, phase- cold and
feat, the patient with standard cancer in
232
00:21:29.759 --> 00:21:34.039
two thousand twenty a year is worth
twenty comma two million pesos, which today
233
00:21:34.279 --> 00:21:38.599
represents about twenty- six million average
of treatment per person per year. If
234
00:21:38.640 --> 00:21:44.759
the disease is already detected in metastases, it could cost up to$ 229
235
00:21:44.759 --> 00:21:48.200
million. According to Cruz, there
may be even higher costs, such as
236
00:21:48.319 --> 00:21:52.319
experimental treatments, which can cost$
10, 000 a month or last-
237
00:21:52.960 --> 00:21:59.319
line treatments. But in addition,
the country allocates nearly ten eight billion a
238
00:21:59.319 --> 00:22:04.039
year in resources to care for cancer
patients. According to figures from the National
239
00:22:04.119 --> 00:22:08.279
Cancer Institute. In Colombia, about
eighty- one thousand and five hundred ninety
240
00:22:08.759 --> 00:22:12.799
- six new cases of cancer are
detected each year and about forty- three
241
00:22:12.839 --> 00:22:18.599
hundred people die each year on account
of that disease. According to a report
242
00:22:18.680 --> 00:22:23.160
of the epidomiological panorama of anif cancer
and according to the data provided in the
243
00:22:23.240 --> 00:22:27.839
high cost account. It is evident
that for cancers with higher mortality and incidence
244
00:22:29.039 --> 00:22:34.119
mom and prostate, the national indicator
of early detection decreased. That same report
245
00:22:34.359 --> 00:22:40.000
shows another problem for Oro Comillas.
On the one hand, there are limitations
246
00:22:40.039 --> 00:22:45.039
in access for certain departments and that
in recent years the specific expenditure on detection
247
00:22:45.039 --> 00:22:49.400
has decreased, which is reflected in
a smaller proportion of cases identified in the
248
00:22:49.480 --> 00:22:56.680
early Cierro Comillas age. The document
concludes that Horo Comillas, Colombia, is
249
00:22:56.759 --> 00:23:00.920
a country whose expenditure on the disease
is mainly focusing on diagnosis and treatment but
250
00:23:00.039 --> 00:23:07.119
not on early detection. This has
a negative impact. Not only about the
251
00:23:07.279 --> 00:23:11.359
lives of patients with this disease,
but it ends up imposing high costs for
252
00:23:11.440 --> 00:23:18.039
stan closing quotes. Looking at the
picture, I have one question about how
253
00:23:18.119 --> 00:23:22.200
well or how badly Colombia is in
the fight against cancer. After that,
254
00:23:22.440 --> 00:23:26.000
I will give the question to the
former Minister of Health, Alejandro Gavilla,
255
00:23:26.599 --> 00:23:30.599
who was also a cancer patient and
he told me this. Colombia has a
256
00:23:30.839 --> 00:23:37.599
cancer prevalence of approximately 6 percent six
out of every 100 people suffering from cancer.
257
00:23:37.480 --> 00:23:42.759
This has been similar to the average
number of Latin American countries. Colombia
258
00:23:42.839 --> 00:23:48.720
to implement successful preventive policies against cancer. The most important, the most successful
259
00:23:48.799 --> 00:23:52.279
has been the anti- smoking policy, which has led to a reduction in
260
00:23:52.400 --> 00:23:56.240
the incidence of tobacco use by approximately
500, 000 people in recent years,
261
00:23:56.799 --> 00:24:02.079
a fact that has had a positive
impact, for obvious reasons, on cancer
262
00:24:02.079 --> 00:24:06.759
control. Colombia, with regard to
treatments, has also made decisive progress in
263
00:24:06.880 --> 00:24:11.200
what is known as financial protection.
Unlike in many Latin American countries, a
264
00:24:11.200 --> 00:24:14.880
low- income family in Colombia does
not have to borrow or sell its home
265
00:24:14.880 --> 00:24:21.440
to pay for cancer treatment. The
coverage of the system of more than ninety
266
00:24:21.799 --> 00:24:25.119
- five percent has, of course, been instrumental for this to happen.
267
00:24:25.480 --> 00:24:29.519
There are still difficulties and problems.
This should be recognized in the opportunity of
268
00:24:29.599 --> 00:24:33.440
treatment in two periods, the time
between the suspicion of diagnosis and the definitive
269
00:24:33.400 --> 00:24:40.839
diagnosis and the time between the definitive
diagnosis and the beginning of treatment. After
270
00:24:40.880 --> 00:24:45.279
finishing my treatment, against a non- hotking report, being Minister of Health
271
00:24:45.400 --> 00:24:48.119
and being an exercise that is anecdotal, but can be illustrative, we found
272
00:24:48.640 --> 00:24:52.799
two patients from the subsidized regimen,
a milkman from the municipality of ubate and
273
00:24:52.839 --> 00:24:57.640
a domestic employee who had been diagnosed
the same day by the same disease.
274
00:24:57.920 --> 00:25:02.759
I started treatment one hundred and twenty
days later they, on average, started
275
00:25:02.799 --> 00:25:08.039
treatment between forty and forty- five
days later the three of us finished treatment
276
00:25:08.160 --> 00:25:15.720
successfully and seven months after the treatment
started, we were declared on permission on
277
00:25:15.759 --> 00:25:22.319
February 4, World Cancer Day was
commemorated. A few days later a close
278
00:25:22.440 --> 00:25:26.160
friend died from this disease, but
he was not the first. I disagree
279
00:25:26.200 --> 00:25:30.119
with this claim that a dying cancer
patient lost the battle against the disease.
280
00:25:32.680 --> 00:25:37.000
I think it' s more of
a battle that we should all give as
281
00:25:37.079 --> 00:25:40.319
a species from the trench of science. It' s a cruel disease,
282
00:25:40.680 --> 00:25:44.720
but I' m sure that just
as we get to the moon and divide
283
00:25:44.799 --> 00:25:45.559
the atom, we' re also
going to be able to find a solution.
284
00:25:47.839 --> 00:25:51.440
But I don' t want to
leave without hearing the testimony of a
285
00:25:51.519 --> 00:25:53.079
person who has suffered from this disease. So I looked for Diana Buitrago,
286
00:25:53.440 --> 00:25:57.880
a cheerleader who' s been around
for several months with a fibroadenoma on her
287
00:25:57.920 --> 00:26:03.799
right zero, I asked her to
tell us how she' s changed her
288
00:26:03.920 --> 00:26:07.319
life to UFFF I feel the emotional
part is the strongest. Not because you
289
00:26:07.359 --> 00:26:11.319
barely read the word to Carcinoma and
googlea, because I thought I was going
290
00:26:11.359 --> 00:26:14.759
to die and I thought it was
my son. Nothing. The first thing
291
00:26:14.880 --> 00:26:18.160
he did was like starting a notebook
and I said" hue puche" if
292
00:26:18.200 --> 00:26:19.240
I remember, because I left something
for him and right now. I realize
293
00:26:19.279 --> 00:26:25.960
that since there are many treatments,
there are many researches and the chances of
294
00:26:26.079 --> 00:26:30.119
survival are too high. Look,
there was something very, very curious going
295
00:26:30.200 --> 00:26:34.599
on, and it' s that
the first week of the diagnosis I couldn
296
00:26:34.680 --> 00:26:37.960
' t sleep and I was feeling
a cold here on the back and I
297
00:26:38.000 --> 00:26:44.279
was saying poached egg is the death
that' s here next to me breathing
298
00:26:44.359 --> 00:26:48.519
in my back, but then I
really realized the simple fact of being alive
299
00:26:48.519 --> 00:26:53.119
means that death is there next to
whispering, because we can die coming down
300
00:26:53.279 --> 00:26:55.680
the stairs in the shower, a
car or a robbery. I don'
301
00:26:56.039 --> 00:26:57.640
t know there' s a thousand
ways to die. So I feel like
302
00:26:57.759 --> 00:27:02.039
cancer was like that cube, although
you' re gonna understand that, yeah,
303
00:27:02.279 --> 00:27:04.440
you' re here right now,
but you don' t know if
304
00:27:04.440 --> 00:27:07.480
you' re gonna be here tomorrow. Then I started doing the things I
305
00:27:07.519 --> 00:27:11.119
felt sorry for doing, I started
dressing the way I liked it. I
306
00:27:11.160 --> 00:27:14.039
would have liked to dress, but
I felt sorry because I said, because
307
00:27:14.079 --> 00:27:15.559
no one dresses like that. Or
and I started to do it because,
308
00:27:17.000 --> 00:27:18.759
because I die And what is it, because here it won' t matter
309
00:27:18.799 --> 00:27:22.240
to anything and to me it'
s the only one that I' m
310
00:27:22.559 --> 00:27:26.160
going to say garlic puja I didn' t and I started to think more
311
00:27:26.160 --> 00:27:30.839
about priorities. My priorities used to
be very focused on each other. They
312
00:27:30.960 --> 00:27:36.599
' re still there, but right
now, I' m before me then
313
00:27:36.920 --> 00:27:42.519
like the most important thing was to
prioritize myself and give the real importance to
314
00:27:42.759 --> 00:27:48.039
the things that deserve it time with
the people that I love not leaving anything
315
00:27:48.119 --> 00:27:49.519
for tomorrow, that is, I
know it sounds super cliche. I'
316
00:27:49.599 --> 00:27:53.720
m in that process that for medicine
and all that, because apparently, there
317
00:27:53.799 --> 00:27:57.559
is a tomorrow, but that'
s like giving the real importance here the
318
00:27:57.640 --> 00:28:06.160
time. I am Roberto Pombo and
this was chapter seventy- eight of my
319
00:28:06.240 --> 00:28:11.079
questions. See you in the next
chapter from now on. This chapter of
320
00:28:11.160 --> 00:28:18.599
my questions is available on all podcast
platforms. This episode was made possible by
321
00:28:18.799 --> 00:28:25.880
Kafam, inspiring Smiles. Dirección Roberto
Pombo, Producción General, juan Abel Gutiérrez,
322
00:28:26.279 --> 00:28:30.960
editorial advisor, Daniel San Pedro Espina, scripts juan Abel Gutiérrez and Johnny
323
00:28:30.039 --> 00:28:37.680
RodrÃguez. Field production Marcela Salazar and
LucÃa Beltrán. Post- production of audio Carlos Bernar
1
00:00:01.080 --> 00:00:06.599
The day to day is full of
urgent news, noise, polemics and fanfare.
2
00:00:06.599 --> 00:00:11.240
But for the quiet, the analysis
and what we like to call slow
3
00:00:11.439 --> 00:00:18.719
- cooking journalism are my questions.
A half- hurry program made by KFAM
4
00:00:19.079 --> 00:00:32.280
inspiring smiles. It is predicted that
by two thousand and fifty cancer cases will
5
00:00:32.320 --> 00:00:37.479
increase by seventy- seven percent.
Finding a cure for this disease seems to
6
00:00:37.560 --> 00:00:41.840
be the cause of the human species. What are the treatments that exist today,
7
00:00:41.960 --> 00:00:47.159
why we have not been able to
find a cure for this chapter.
8
00:00:47.479 --> 00:00:54.479
We spoke with radiologist Germán Arango,
with former Health Minister Alejandro Gaviria. Rafael
9
00:00:54.560 --> 00:01:00.560
Sánchez Paris, Executive Director of the
Center for Cancer Treatment and Research, Scarlos
10
00:01:00.600 --> 00:01:06.719
Sarmiento Angulo and Lina MarÃa Trujillo,
Deputy Director of Medical Care and Teaching at
11
00:01:06.760 --> 00:01:11.840
the National Cancer Institute. I am
Roberto Pombo and this is chapter seventy-
12
00:01:12.000 --> 00:01:19.359
eight of my questions. Welcome.
The human has taken all his history,
13
00:01:19.840 --> 00:01:25.760
understanding himself, the world around him
and the connection between all. Since the
14
00:01:25.879 --> 00:01:30.799
arbors of our conscience, we have
asked ourselves questions and it was not enough
15
00:01:30.879 --> 00:01:34.040
for us to be bipeds and to
have opposable thumbs. We have explored the
16
00:01:34.439 --> 00:01:38.840
world all its seas and depths,
volcanoes and its wild force and glaciers,
17
00:01:40.120 --> 00:01:47.519
jungle deserts. We study every species
with which we share the planet at some
18
00:01:47.599 --> 00:01:49.239
point in history. It wasn'
t enough for us what was around us.
19
00:01:49.760 --> 00:01:55.599
Then we looked up and looked for
explanations to what was beyond our reach
20
00:01:55.640 --> 00:02:00.920
at the time. So someone once
created a device to find out what those
21
00:02:00.040 --> 00:02:05.920
lights were all about, shining in
what we call heaven. We saw them
22
00:02:06.000 --> 00:02:10.800
moving at a pace we could predict. Then we gave them names, finding
23
00:02:10.840 --> 00:02:15.199
their characteristics. We realized our place
in the Universe, the immensity and infinity,
24
00:02:16.000 --> 00:02:23.000
of what was beyond the earth.
We have found explanations for the universe,
25
00:02:23.319 --> 00:02:28.879
its galaxies, black holes, nebulae
and stars. All that wasn'
26
00:02:29.000 --> 00:02:31.280
t enough for us. And just
as someone created a telescope to see and
27
00:02:31.360 --> 00:02:37.439
understand what was at distances and times
almost impossible to reach. Someone created a
28
00:02:37.479 --> 00:02:43.840
microscope to see what was inside us. So we did the same thing at
29
00:02:43.840 --> 00:02:46.159
quantum level, that is, not
outwards, but inwards, at the level
30
00:02:46.159 --> 00:02:52.560
of molecules and atoms. At one
point we said that that was the limit
31
00:02:52.560 --> 00:02:55.599
point, which was indivisible, the
micro thing that existed. However, as
32
00:02:55.840 --> 00:03:00.080
it seems, custom was temporary to
and someone else discovered that it could be
33
00:03:00.159 --> 00:03:07.159
seen beyond the atom and later divided
it. I am dazzled to see the
34
00:03:07.199 --> 00:03:09.960
level of knowledge we have acquired as
a species. It will seem that there
35
00:03:10.039 --> 00:03:15.120
is nothing impossible for this wonderful species
that we are, with its lights and
36
00:03:15.120 --> 00:03:19.000
shadows. And although out there,
in space so far and on a macro
37
00:03:19.120 --> 00:03:23.879
scale, there are aspects that seem
to overcome us and determine our existence,
38
00:03:24.080 --> 00:03:30.120
although around us there are depths and
elements that threaten our existence. It is
39
00:03:30.199 --> 00:03:34.479
at the atomic level within us that
there is a phenomenon that owns our fears
40
00:03:34.560 --> 00:03:42.560
and that today is a threat to
humanity, cancer cells. Cancer is not
41
00:03:42.599 --> 00:03:46.560
something new. Human beings and other
animals have had cancer throughout history and there
42
00:03:46.599 --> 00:03:53.599
are records of that disease in fossils
and most holy scriptures. Some of the
43
00:03:53.680 --> 00:03:59.159
first cancer tests are among fossilized bone
tumors, human mummies from ancient Egypt,
44
00:03:59.520 --> 00:04:05.120
and ancient manuscripts. For example,
mummies have been found with growths that suggest
45
00:04:05.199 --> 00:04:13.240
bone cancer called hostium sarcoma. The
oldest description you have did not include the
46
00:04:13.280 --> 00:04:16.800
word cancer was discovered in Egypt and
dates back to the year three thousand BC,
47
00:04:16.959 --> 00:04:21.800
in a papyrus known as Papyrus Edwin
Smith, which is part of a
48
00:04:21.920 --> 00:04:27.879
book on trauma surgery and is said
to be the first surgical treatise in history.
49
00:04:29.959 --> 00:04:34.920
This document describes eight cases of breast
tumors or ulcers that were removed by
50
00:04:35.000 --> 00:04:42.639
cauterization with a tool called a fire
drill. The paper says about the disease
51
00:04:43.240 --> 00:04:47.160
there is no treatment. It was
not until the 19th century, when the
52
00:04:47.160 --> 00:04:53.240
anesthesia appeared that the first surgeries were
performed to remove some types of cancer.
53
00:04:53.839 --> 00:04:57.800
But, even though this disease has
shared so much time with humans, understanding
54
00:04:57.800 --> 00:05:02.079
it has not been easy. One
of the many statements that have been made
55
00:05:02.120 --> 00:05:08.800
on the subject is that we all
have cancer cells, but that' s
56
00:05:08.920 --> 00:05:13.959
how we go about parts. This
disease arises from random genetic changes, called
57
00:05:14.040 --> 00:05:20.079
mutations within healthy cells acquired over time. These mutations can occur for several reasons,
58
00:05:20.240 --> 00:05:25.839
such as lifestyle choices, family predispositions, long- term existing health conditions,
59
00:05:26.040 --> 00:05:32.279
or even exposing hazardous chemicals. As
mutated cells build up, they become
60
00:05:32.360 --> 00:05:40.000
cancerous. A cell that is able
to grow without control accumulates errors in its
61
00:05:40.079 --> 00:05:46.199
DNA code, which makes a gene
or set of genes malfunction. If the
62
00:05:46.279 --> 00:05:50.480
cell also loses certain safety mechanisms this
pushes it toward cancer. In other words,
63
00:05:51.199 --> 00:05:56.879
several factors need to come together to
make a cell cancerous. And any
64
00:05:57.000 --> 00:06:00.600
cell in the body has the potential
to do so. It can be divided
65
00:06:01.040 --> 00:06:06.160
if it accumulates errors with certain genes
and if these failures cause it to grow
66
00:06:06.160 --> 00:06:12.519
out of control. According to doctors
Hugur Shain and Oslem Duressi, founders of
67
00:06:12.519 --> 00:06:16.839
the biotechnology company Biontech, these random
genetic changes that occur in cancer cells arise
68
00:06:16.920 --> 00:06:24.120
two implications. The first is that
each cancer is as unique as the individual
69
00:06:24.160 --> 00:06:28.199
it affects, that is, that
even those people who are diagnosed with the
70
00:06:28.279 --> 00:06:33.680
same type of cancer have only a
fraction of shared mutations. And the second
71
00:06:33.759 --> 00:06:39.480
implication is that each tumor is a
intricate tapestry of billions of different cells that
72
00:06:39.480 --> 00:06:45.279
constantly learn to adapt, to evade
the immune system and to resist the therapeutic
73
00:06:45.319 --> 00:06:50.240
strategies that medicine and technology has investigated
And it is that possible cures therapies,
74
00:06:50.879 --> 00:06:58.040
varying shock treatments have not been lacking
in history. Since surgeries to remove tumors,
75
00:06:58.240 --> 00:07:00.639
the use of radiation and official artis
intelligence have been part of human innovation
76
00:07:00.639 --> 00:07:09.759
to combat that inner enemy. I
looked for Dr Rafael Sánchez Paris, Executive
77
00:07:09.879 --> 00:07:14.360
Director of the Cancer Treatment and Research
Center, Juis Carlos Sarmiento Angulou, to
78
00:07:14.399 --> 00:07:18.680
better answer the big question why is
it so difficult to find a cure for
79
00:07:18.759 --> 00:07:26.399
cancer? This he told me,
cancer is not just a disease. It
80
00:07:26.480 --> 00:07:34.399
is a group of really different diseases, caused by factors sometimes different from each
81
00:07:34.519 --> 00:07:41.639
other. Therefore, at the outset
there are some more curable than others.
82
00:07:41.680 --> 00:07:47.160
In addition, today the number of
patients with advanced disease is higher than with
83
00:07:47.279 --> 00:07:55.639
early disease. When cancer is diagnosed
early, the cure percentage is higher and
84
00:07:55.720 --> 00:08:01.480
this is directly related to timely access
to health services and self- care.
85
00:08:05.759 --> 00:08:13.759
Finally, the genomic changes within the
disease are dynamic and progressive. That is,
86
00:08:15.639 --> 00:08:20.680
cells learn to survive the treatments given, which complements treatment over time.
87
00:08:26.120 --> 00:08:31.279
A recent report was published in the
journal b m Jota Oncology, which concludes,
88
00:08:31.720 --> 00:08:35.759
among other things, that the global
incidence of early- onset cancer increased
89
00:08:35.879 --> 00:08:39.120
by seventy- nine comma one percent, and the number of early- oncology
90
00:08:39.159 --> 00:08:45.879
deaths increased by twenty- seven comma
seven percent between one thousand nine hundred ninety
91
00:08:46.240 --> 00:08:50.080
- two thousand nineteen. In more
concise terms, the number of people under
92
00:08:50.120 --> 00:08:54.639
the age of 50 diagnosed with this
disease worldwide has increased by almost eighty percent
93
00:08:54.879 --> 00:09:01.080
in the last three decades alone,
and the findings of the study do not
94
00:09:01.080 --> 00:09:07.360
stop there. Projections indicated that the
overall number of incidences and deaths from early
95
00:09:07.879 --> 00:09:11.759
- onset cancer would increase by thirty- one percent and twenty- one percent
96
00:09:11.879 --> 00:09:16.519
by two thousand thirty, respectively.
And excuse me for all the bad news.
97
00:09:16.600 --> 00:09:20.840
But, according to the World Health
Organization, more than thirty- five
98
00:09:20.879 --> 00:09:24.480
million new cases are predicted for two
thousand fifty, an increase of seventy-
99
00:09:24.000 --> 00:09:28.799
seven percent, compared with the estimated
twenty million cases for two thousand twenty-
100
00:09:28.279 --> 00:09:35.399
two. All these figures of the
rapidly growing global burden of cancer reflect the
101
00:09:35.519 --> 00:09:41.639
ageing and growth of the world population, as well as changes in people'
102
00:09:41.759 --> 00:09:45.720
s exposure to risk factors of which
several are associated with socio- economic development.
103
00:09:48.879 --> 00:09:54.320
All these numbers for the future are
not encouraging A little over a month
104
00:09:54.320 --> 00:09:58.600
ago, the International Agency for Cancer
Research published the latest estimates of the global
105
00:09:58.679 --> 00:10:05.000
burden of cancer, in which they
found data like First, in only two
106
00:10:05.080 --> 00:10:09.039
thousand twenty- two there were twenty
million new cases and nine seven million deaths
107
00:10:09.039 --> 00:10:16.600
from this disease. Second, about
one in five people develop cancer throughout their
108
00:10:16.679 --> 00:10:20.600
lives and finally, about one in
nine men and one in twelve women die
109
00:10:20.799 --> 00:10:30.279
from the disease. All these numbers
of such impressive proportions leave me with many
110
00:10:30.279 --> 00:10:35.639
questions, but especially one way to
reverse all these estimates about the future incidence
111
00:10:35.720 --> 00:10:41.159
of cancer. I looked for arina
MarÃa Trujillo and assistant director of medical care
112
00:10:41.200 --> 00:10:46.120
and teaching at the National Cancer Institute. To answer this, he told me
113
00:10:46.200 --> 00:10:50.360
the first thing is to declare that
cancer is not a single disease. It
114
00:10:50.440 --> 00:10:56.159
is a word that groups different diseases
that have different origins, different causalities and,
115
00:10:56.399 --> 00:11:01.440
by that of different approach, not
only of annassic treatment, then there
116
00:11:01.440 --> 00:11:05.919
is no common strategy. The only
thing we could talk about is that we
117
00:11:05.039 --> 00:11:11.480
could change in a relatively feasible time
frame according to the calculations of interim neck
118
00:11:11.480 --> 00:11:16.600
cancer, cancer whose torino has a
global elimination strategy that, in fact,
119
00:11:16.759 --> 00:11:22.200
Cartagena is the headquarters of the Global
Forum on the Elimination of Cervical Cancer,
120
00:11:22.440 --> 00:11:26.559
in which three strategies are proposed.
Thanks to the fact that with terino neck
121
00:11:26.639 --> 00:11:31.120
cancer we know who produces it,
we have tools to diagnose it before it
122
00:11:31.200 --> 00:11:33.080
becomes cancer and we have how to
treat it properly. Once it' s
123
00:11:33.159 --> 00:11:37.720
a cancer, which we have to
prevent, vaccines against the human papillomavirus,
124
00:11:37.039 --> 00:11:41.320
which is the causal people, which
we have to diagnose in a timely manner
125
00:11:41.360 --> 00:11:46.000
before it' s a cancer,
papilloma virus tests and psitologies and we have
126
00:11:46.080 --> 00:11:50.919
how to treat it. Colombia has
enough staff and enough technology to cope with
127
00:11:52.039 --> 00:11:58.159
the different stages of cancer of Colombian
women, although cancer, as it already
128
00:11:58.200 --> 00:12:03.440
says, is an anti- disease
to what this alarming increase is due to,
129
00:12:03.639 --> 00:12:07.799
According to the authors of the study
published in bm J, oncology.
130
00:12:07.120 --> 00:12:11.279
Genetic factors are likely to influence,
but diets rich in meat, red and
131
00:12:11.399 --> 00:12:16.320
salt and low without fruits and milk, in addition to alcohol and tobacco consumption,
132
00:12:16.440 --> 00:12:20.240
are the main risk factors behind the
most common cancers among those under 50
133
00:12:20.360 --> 00:12:24.440
years of age, in addition to
physical inactivity, excess weight and high blood
134
00:12:24.480 --> 00:12:31.720
sugar levels. According to this research, I quote the changes in diet,
135
00:12:33.159 --> 00:12:35.799
lifestyle and environment since the beginning of
the 20th century that have led to an
136
00:12:35.799 --> 00:12:43.840
increase in rates and obesity. Physical
inactivity, Westernized diets, and environmental pollution
137
00:12:43.879 --> 00:12:48.279
may have affected the incidence of early
onset cancer. In addition, alcohol,
138
00:12:48.639 --> 00:12:56.480
smoking and harmful exposures during pregnancy may
also have affected closing quotes and make a
139
00:12:56.559 --> 00:13:01.120
lot of sense. Just think about
how I change the human' s life,
140
00:13:01.159 --> 00:13:03.639
his work routines, or the way
we feed or consume products such as
141
00:13:03.720 --> 00:13:11.000
alcohol, nicotine, or ultraprocessed edibles. On the latter, a study by
142
00:13:11.000 --> 00:13:16.600
the University of Viennam in collaboration with
the International Agency for Cancer Research found that
143
00:13:16.600 --> 00:13:20.279
the higher the consumption of ultraprocessed foods, the greater the risk of suffering a
144
00:13:20.399 --> 00:13:28.279
combination of chronic diseases such as cancer, diabetes or heart disease. Another of
145
00:13:28.320 --> 00:13:33.240
these changes in modern life that have
helped to increase cases of this disease is
146
00:13:33.279 --> 00:13:39.919
air pollution, as if global warming
was no longer enough. At the presidential
147
00:13:39.000 --> 00:13:45.919
symposium itself two thousand twenty- two, Professor Charles Schanton of the Francis Creek
148
00:13:45.919 --> 00:13:50.080
Institute, a biomedical research center in
London, presented an investigation that highlighted that
149
00:13:50.159 --> 00:13:56.440
the same particles that contribute to climate
change are impacting human health through an important
150
00:13:56.440 --> 00:14:03.360
mechanism that causes cancer in lung cells. The Lancet Commission on Pollution and Health
151
00:14:03.679 --> 00:14:07.120
established that all forms of pollution cause
forty- three percent of lung cancer deaths.
152
00:14:09.720 --> 00:14:13.679
Air pollution alone causes twenty- nine
percent of all lung cancer deaths and
153
00:14:13.679 --> 00:14:18.399
clear estimates give, according to WHO, ninety- nine percent are breathing unhealthy
154
00:14:18.399 --> 00:14:26.399
air. As Dr Emmanuel Ricard told
him by the voice of the French League
155
00:14:26.600 --> 00:14:31.759
against Cancer in the medium Frans van
Cat, it is mainly about pollution by
156
00:14:31.840 --> 00:14:37.440
fine particles and the gases emitted by
the saying are one of the main sources
157
00:14:37.440 --> 00:14:41.480
of these particles. However, a
study published in the British journal of cancer,
158
00:14:41.960 --> 00:14:48.440
the greatest risk factor for most cancers
is simply aging. According to the
159
00:14:48.519 --> 00:14:54.200
study, more than three quarters of
all people diagnosed with this disease in the
160
00:14:54.320 --> 00:14:58.559
UK are sixty years of age or
older, and this is because cancer is
161
00:14:58.639 --> 00:15:03.559
a disease of our genes. Fragments
of the DNA Code that contain instructions for
162
00:15:03.639 --> 00:15:09.360
all microscopic machinery within our cells and
over time, errors accumulate in this code
163
00:15:09.600 --> 00:15:13.600
and scientists can now see them imprinted
on the cancer DNA, and it is
164
00:15:13.639 --> 00:15:20.200
these errors that can drive a cell' s journey. They are reached,
165
00:15:22.759 --> 00:15:26.720
but not all are bad news.
According to the nation' s annual report
166
00:15:26.720 --> 00:15:31.039
on the cancer situation in general,
mortality rates for this disease decreased by an
167
00:15:31.120 --> 00:15:35.679
average of two comma three per cent
per year among men and an average of
168
00:15:35.759 --> 00:15:41.399
one comma nine per cent per year
among women. The overall cancer mortality rate
169
00:15:41.480 --> 00:15:46.039
in the United States declined by one
third between one thousand nine hundred and ninety
170
00:15:46.279 --> 00:15:50.080
- one and two thousand nineteen.
This is largely because fewer people smoke and
171
00:15:50.120 --> 00:15:54.759
develop lung cancer, also because as
screening tests, prevention and treatments have improved
172
00:15:54.799 --> 00:16:00.039
for all types of cancer it is, this decrease has continued and even accelerated.
173
00:16:03.039 --> 00:16:08.039
The national cancer mortality rate is falling
by about two percent each year and
174
00:16:08.120 --> 00:16:15.639
in Colombia the survival of childhood cancer
is sixty percent. Early detection is one
175
00:16:15.720 --> 00:16:19.840
of the ways in which it can
help more people survive this disease and for
176
00:16:19.840 --> 00:16:26.120
this purpose, it seems that artificial
intelligence can play a key role. It
177
00:16:26.240 --> 00:16:30.559
couldn' t be used just to
make fake videos of politicians. And that
178
00:16:30.600 --> 00:16:36.720
' s because, according to research
published in The Lancet Oncology suggests that artificial
179
00:16:36.799 --> 00:16:41.960
intelligence could diagnose cancer with twice as
much accuracy as a doctor' s biopsy.
180
00:16:45.159 --> 00:16:48.360
I looked for radiologist Germán Arango,
who already uses this technology for medical
181
00:16:48.440 --> 00:16:53.519
purposes, and asked him how artificial
intelligence can help detect cancer in a timely
182
00:16:53.559 --> 00:17:00.120
manner. This he told me.
Artificial intelligence can be significantly helped in early
183
00:17:00.159 --> 00:17:06.279
detection of cancer through various methods and
applications. The first and most important of
184
00:17:06.359 --> 00:17:11.279
these is in the analysis of diagnostic
medical images, where, especially deep learning
185
00:17:11.400 --> 00:17:18.200
has shown remarkable effectiveness in the analysis
of diagnostic medical images. Like MRIs,
186
00:17:19.039 --> 00:17:25.759
CT scans, mammograms, X-
rays. Artificial intelligence algorithms can detect abnormalities
187
00:17:25.799 --> 00:17:30.640
in images that can be indicative of
cancer, often with the accuracy that equals
188
00:17:30.720 --> 00:17:36.599
or exceeds that of human specialists.
Here it is important to highlight a new
189
00:17:36.720 --> 00:17:41.519
technique, which is total body resonance
or diamar powder, which is an advanced
190
00:17:41.559 --> 00:17:45.160
imaging technique that allows you to obtain
detailed images of the whole body in a
191
00:17:45.160 --> 00:17:49.319
single exposure, being especially valuable in
the early detection of cancer. The editing
192
00:17:49.359 --> 00:17:55.799
of artificial intelligence to the diagnostic process
of this technique substantially increases its performance and
193
00:17:55.799 --> 00:17:59.559
accuracy, taking into account that it
generates large volumes of information. Other fronts
194
00:17:59.599 --> 00:18:06.039
where artificial intelligence contributes to the early
diagnosis of cancer. These are pattern analyses,
195
00:18:06.559 --> 00:18:11.720
assisted diagnosis, personalization of detection,
research and development, and continuous dying.
196
00:18:12.759 --> 00:18:17.680
In short, artificial interedency is transforming
the field of ecological diagnosis, improving
197
00:18:17.839 --> 00:18:22.200
accuracy and efficiency in early scope detection, which can lead to better prognosis and
198
00:18:22.200 --> 00:18:32.319
higher survival rates for patients. Attempts
to overcome this disease do not begin or
199
00:18:32.440 --> 00:18:37.640
end with artificial intelligence. From surgery
to chemotherapy, treatments have become more friendly
200
00:18:37.640 --> 00:18:42.599
or less invasive. For example,
if someone was diagnosed with breast cancer 100
201
00:18:42.640 --> 00:18:48.079
years ago, doctors had to take
drastic measures, such as removing the entire
202
00:18:48.119 --> 00:18:52.039
breast, along with the underlying pectoral
muscles and all the lymph nodes in the
203
00:18:52.079 --> 00:18:57.799
armpit. However, in nineteen hundred
and sixty, a type of surgery was
204
00:18:57.920 --> 00:19:03.359
discovered that was less invasive or snomizing
the side effects. The same has happened
205
00:19:03.400 --> 00:19:07.680
with other treatments, such as radiation
therapy and chemotherapy, which over time have
206
00:19:07.839 --> 00:19:14.640
refined and refined their procedures to minimize
side effects. And, as I mentioned
207
00:19:14.720 --> 00:19:18.680
before, as well as our faces
and our actillary footprints, each case of
208
00:19:18.759 --> 00:19:23.559
cancer is unique. Researchers have discovered
many ways to reduce the negative impacts of
209
00:19:23.640 --> 00:19:29.960
treatments, adapting them to individual needs
such as modulated intensity radiation therapy, in
210
00:19:29.960 --> 00:19:33.960
which radiation rays vary in intensity strength, allowing them to shape to point to
211
00:19:33.000 --> 00:19:37.359
a precise area, either in the
exact form of a tumor, if used
212
00:19:37.400 --> 00:19:41.160
to reduce it before surgery, or
the immediate area around where there was until
213
00:19:41.359 --> 00:19:48.759
the last. In fact, the
pandemic left something good and it was that
214
00:19:48.799 --> 00:19:55.079
research to develop the vaccine against covid
nineteen inspired the use of this same molecule
215
00:19:55.160 --> 00:20:00.440
to create a vaccine against pancras cancer. Last year the results of the first
216
00:20:00.480 --> 00:20:03.880
trials in patients, a group of
sixteen people in a first batch of trials
217
00:20:03.920 --> 00:20:11.799
showed promising results. Fifty percent of
the patients had positive results for this trial
218
00:20:11.839 --> 00:20:18.599
had to create a personalized vaccine for
each patient. However, and even though
219
00:20:18.599 --> 00:20:22.160
different treatments have been tried for the
many types of cancer, accessing them is
220
00:20:22.440 --> 00:20:30.200
not always easy. The WHO Global
Survey on Universal Health Coverage and Cancer shows
221
00:20:30.279 --> 00:20:33.400
that only thirty- nine per cent
of participating countries covered basic aspects of cancer
222
00:20:33.480 --> 00:20:38.079
management as part of their basic health
services funded for all citizens, health benefit
223
00:20:38.160 --> 00:20:44.160
packages, and only 28 per cent
of participating countries additionally covered care for people
224
00:20:44.160 --> 00:20:48.359
in need of palliative care, including
pain relief in general, and not just
225
00:20:48.400 --> 00:20:59.079
cancer- related care. The case
of Colombia is not the worst, but
226
00:20:59.160 --> 00:21:02.519
neither is the best. According to
an article by the University of Rosario,
227
00:21:03.000 --> 00:21:07.519
cancer mortality rates are higher in Colombia
due to greater barriers to early diagnosis,
228
00:21:07.920 --> 00:21:11.599
which is that mortality rates are higher
in middle- and low- income countries,
229
00:21:11.799 --> 00:21:15.480
which shows that there are fewer preventive
actions and greater access barriers to diagnosis
230
00:21:15.599 --> 00:21:25.000
and early initiation of treatment. According
to the newspaper, La República with data
231
00:21:25.039 --> 00:21:29.720
from ASEMI, phase- cold and
feat, the patient with standard cancer in
232
00:21:29.759 --> 00:21:34.039
two thousand twenty a year is worth
twenty comma two million pesos, which today
233
00:21:34.279 --> 00:21:38.599
represents about twenty- six million average
of treatment per person per year. If
234
00:21:38.640 --> 00:21:44.759
the disease is already detected in metastases, it could cost up to$ 229
235
00:21:44.759 --> 00:21:48.200
million. According to Cruz, there
may be even higher costs, such as
236
00:21:48.319 --> 00:21:52.319
experimental treatments, which can cost$
10, 000 a month or last-
237
00:21:52.960 --> 00:21:59.319
line treatments. But in addition,
the country allocates nearly ten eight billion a
238
00:21:59.319 --> 00:22:04.039
year in resources to care for cancer
patients. According to figures from the National
239
00:22:04.119 --> 00:22:08.279
Cancer Institute. In Colombia, about
eighty- one thousand and five hundred ninety
240
00:22:08.759 --> 00:22:12.799
- six new cases of cancer are
detected each year and about forty- three
241
00:22:12.839 --> 00:22:18.599
hundred people die each year on account
of that disease. According to a report
242
00:22:18.680 --> 00:22:23.160
of the epidomiological panorama of anif cancer
and according to the data provided in the
243
00:22:23.240 --> 00:22:27.839
high cost account. It is evident
that for cancers with higher mortality and incidence
244
00:22:29.039 --> 00:22:34.119
mom and prostate, the national indicator
of early detection decreased. That same report
245
00:22:34.359 --> 00:22:40.000
shows another problem for Oro Comillas.
On the one hand, there are limitations
246
00:22:40.039 --> 00:22:45.039
in access for certain departments and that
in recent years the specific expenditure on detection
247
00:22:45.039 --> 00:22:49.400
has decreased, which is reflected in
a smaller proportion of cases identified in the
248
00:22:49.480 --> 00:22:56.680
early Cierro Comillas age. The document
concludes that Horo Comillas, Colombia, is
249
00:22:56.759 --> 00:23:00.920
a country whose expenditure on the disease
is mainly focusing on diagnosis and treatment but
250
00:23:00.039 --> 00:23:07.119
not on early detection. This has
a negative impact. Not only about the
251
00:23:07.279 --> 00:23:11.359
lives of patients with this disease,
but it ends up imposing high costs for
252
00:23:11.440 --> 00:23:18.039
stan closing quotes. Looking at the
picture, I have one question about how
253
00:23:18.119 --> 00:23:22.200
well or how badly Colombia is in
the fight against cancer. After that,
254
00:23:22.440 --> 00:23:26.000
I will give the question to the
former Minister of Health, Alejandro Gavilla,
255
00:23:26.599 --> 00:23:30.599
who was also a cancer patient and
he told me this. Colombia has a
256
00:23:30.839 --> 00:23:37.599
cancer prevalence of approximately 6 percent six
out of every 100 people suffering from cancer.
257
00:23:37.480 --> 00:23:42.759
This has been similar to the average
number of Latin American countries. Colombia
258
00:23:42.839 --> 00:23:48.720
to implement successful preventive policies against cancer. The most important, the most successful
259
00:23:48.799 --> 00:23:52.279
has been the anti- smoking policy, which has led to a reduction in
260
00:23:52.400 --> 00:23:56.240
the incidence of tobacco use by approximately
500, 000 people in recent years,
261
00:23:56.799 --> 00:24:02.079
a fact that has had a positive
impact, for obvious reasons, on cancer
262
00:24:02.079 --> 00:24:06.759
control. Colombia, with regard to
treatments, has also made decisive progress in
263
00:24:06.880 --> 00:24:11.200
what is known as financial protection.
Unlike in many Latin American countries, a
264
00:24:11.200 --> 00:24:14.880
low- income family in Colombia does
not have to borrow or sell its home
265
00:24:14.880 --> 00:24:21.440
to pay for cancer treatment. The
coverage of the system of more than ninety
266
00:24:21.799 --> 00:24:25.119
- five percent has, of course, been instrumental for this to happen.
267
00:24:25.480 --> 00:24:29.519
There are still difficulties and problems.
This should be recognized in the opportunity of
268
00:24:29.599 --> 00:24:33.440
treatment in two periods, the time
between the suspicion of diagnosis and the definitive
269
00:24:33.400 --> 00:24:40.839
diagnosis and the time between the definitive
diagnosis and the beginning of treatment. After
270
00:24:40.880 --> 00:24:45.279
finishing my treatment, against a non- hotking report, being Minister of Health
271
00:24:45.400 --> 00:24:48.119
and being an exercise that is anecdotal, but can be illustrative, we found
272
00:24:48.640 --> 00:24:52.799
two patients from the subsidized regimen,
a milkman from the municipality of ubate and
273
00:24:52.839 --> 00:24:57.640
a domestic employee who had been diagnosed
the same day by the same disease.
274
00:24:57.920 --> 00:25:02.759
I started treatment one hundred and twenty
days later they, on average, started
275
00:25:02.799 --> 00:25:08.039
treatment between forty and forty- five
days later the three of us finished treatment
276
00:25:08.160 --> 00:25:15.720
successfully and seven months after the treatment
started, we were declared on permission on
277
00:25:15.759 --> 00:25:22.319
February 4, World Cancer Day was
commemorated. A few days later a close
278
00:25:22.440 --> 00:25:26.160
friend died from this disease, but
he was not the first. I disagree
279
00:25:26.200 --> 00:25:30.119
with this claim that a dying cancer
patient lost the battle against the disease.
280
00:25:32.680 --> 00:25:37.000
I think it' s more of
a battle that we should all give as
281
00:25:37.079 --> 00:25:40.319
a species from the trench of science. It' s a cruel disease,
282
00:25:40.680 --> 00:25:44.720
but I' m sure that just
as we get to the moon and divide
283
00:25:44.799 --> 00:25:45.559
the atom, we' re also
going to be able to find a solution.
284
00:25:47.839 --> 00:25:51.440
But I don' t want to
leave without hearing the testimony of a
285
00:25:51.519 --> 00:25:53.079
person who has suffered from this disease. So I looked for Diana Buitrago,
286
00:25:53.440 --> 00:25:57.880
a cheerleader who' s been around
for several months with a fibroadenoma on her
287
00:25:57.920 --> 00:26:03.799
right zero, I asked her to
tell us how she' s changed her
288
00:26:03.920 --> 00:26:07.319
life to UFFF I feel the emotional
part is the strongest. Not because you
289
00:26:07.359 --> 00:26:11.319
barely read the word to Carcinoma and
googlea, because I thought I was going
290
00:26:11.359 --> 00:26:14.759
to die and I thought it was
my son. Nothing. The first thing
291
00:26:14.880 --> 00:26:18.160
he did was like starting a notebook
and I said" hue puche" if
292
00:26:18.200 --> 00:26:19.240
I remember, because I left something
for him and right now. I realize
293
00:26:19.279 --> 00:26:25.960
that since there are many treatments,
there are many researches and the chances of
294
00:26:26.079 --> 00:26:30.119
survival are too high. Look,
there was something very, very curious going
295
00:26:30.200 --> 00:26:34.599
on, and it' s that
the first week of the diagnosis I couldn
296
00:26:34.680 --> 00:26:37.960
' t sleep and I was feeling
a cold here on the back and I
297
00:26:38.000 --> 00:26:44.279
was saying poached egg is the death
that' s here next to me breathing
298
00:26:44.359 --> 00:26:48.519
in my back, but then I
really realized the simple fact of being alive
299
00:26:48.519 --> 00:26:53.119
means that death is there next to
whispering, because we can die coming down
300
00:26:53.279 --> 00:26:55.680
the stairs in the shower, a
car or a robbery. I don'
301
00:26:56.039 --> 00:26:57.640
t know there' s a thousand
ways to die. So I feel like
302
00:26:57.759 --> 00:27:02.039
cancer was like that cube, although
you' re gonna understand that, yeah,
303
00:27:02.279 --> 00:27:04.440
you' re here right now,
but you don' t know if
304
00:27:04.440 --> 00:27:07.480
you' re gonna be here tomorrow. Then I started doing the things I
305
00:27:07.519 --> 00:27:11.119
felt sorry for doing, I started
dressing the way I liked it. I
306
00:27:11.160 --> 00:27:14.039
would have liked to dress, but
I felt sorry because I said, because
307
00:27:14.079 --> 00:27:15.559
no one dresses like that. Or
and I started to do it because,
308
00:27:17.000 --> 00:27:18.759
because I die And what is it, because here it won' t matter
309
00:27:18.799 --> 00:27:22.240
to anything and to me it'
s the only one that I' m
310
00:27:22.559 --> 00:27:26.160
going to say garlic puja I didn' t and I started to think more
311
00:27:26.160 --> 00:27:30.839
about priorities. My priorities used to
be very focused on each other. They
312
00:27:30.960 --> 00:27:36.599
' re still there, but right
now, I' m before me then
313
00:27:36.920 --> 00:27:42.519
like the most important thing was to
prioritize myself and give the real importance to
314
00:27:42.759 --> 00:27:48.039
the things that deserve it time with
the people that I love not leaving anything
315
00:27:48.119 --> 00:27:49.519
for tomorrow, that is, I
know it sounds super cliche. I'
316
00:27:49.599 --> 00:27:53.720
m in that process that for medicine
and all that, because apparently, there
317
00:27:53.799 --> 00:27:57.559
is a tomorrow, but that'
s like giving the real importance here the
318
00:27:57.640 --> 00:28:06.160
time. I am Roberto Pombo and
this was chapter seventy- eight of my
319
00:28:06.240 --> 00:28:11.079
questions. See you in the next
chapter from now on. This chapter of
320
00:28:11.160 --> 00:28:18.599
my questions is available on all podcast
platforms. This episode was made possible by
321
00:28:18.799 --> 00:28:25.880
Kafam, inspiring Smiles. Dirección Roberto
Pombo, Producción General, juan Abel Gutiérrez,
322
00:28:26.279 --> 00:28:30.960
editorial advisor, Daniel San Pedro Espina, scripts juan Abel Gutiérrez and Johnny
323
00:28:30.039 --> 00:28:37.680
RodrÃguez. Field production Marcela Salazar and
LucÃa Beltrán. Post- production of audio Carlos Bernar